Fervent and Lobe was a series by writer John Smith about freelance Psilencers Lionel Fervent and Dwayne Lobe, two characters best known as supporting characters in the series Tyranny Rex. The series, which ran in 2000 AD progs 642 to 649 and was subtitled "The Issigri Variations", is effectively a prequel to Smith's long-running Indigo Prime strip.